https://he05.tci-thaijo.org/index.php/CCIT <p><strong>Journal of Central Chest Institute of Thailand</strong></p> <p><strong><em>ISSN: </em></strong><em>1686-6614<strong> E-ISSN:</strong> </em></p> <p><strong><em>Publication Frequency : </em></strong><em>3 issues per year (January-April), (May-August), (September-December).</em></p> <p><strong><em>Aims and Scope: </em></strong><em>Chest Diseases, Cardiovascular Diseases, Critical Care Medicine and Cardiovascular Thoracic Surgery</em></p> สถาบันโรคทรวงอก en-US Journal of Central Chest Institute of Thailand 1686-6614 <ol> <li>เนื้อหาและข้อมูลในบทความที่ลงพิมพ์กับวารสารโรคหัวใจและทรวงอกถือเป็นข้อคิดเห็น และความรับผิดชอบของผู้เขียนบทความโดยตรงซึ่งกองบรรณาธิการวารสารไม่จำเป็นต้องเห็นด้วย หรือร่วมรับผิดชอบใด ๆ</li> <li><span style="font-size: 0.875rem;">บทความ ข้อมูล เนื้อหา รูปภาพ ฯลฯ ที่ได้รับการตีพิมพ์ในวารสารสถาบันโรคทรวงอกถือเป็นลิขสิทธิ์ของวารสารวิชาการ หากบุคคลหรือหน่วยงานใดต้องการนำทั้งหมดหรือส่วนหนึ่ง ส่วนใดไปเผยแพร่ กรุณาอ้างอิงบทความนั้น ๆ</span></li> </ol> https://he05.tci-thaijo.org/index.php/CCIT/article/view/7852 <p><strong>Background: </strong>Severe asthma is a difficult-to-control condition that substantially affects patients’ health-related quality of life (HRQoL). Appropriate symptom management is essential for improving symptom control and promoting favorable health outcomes in patients with severe asthma. <strong>Objectives:</strong> To examine the relationship between symptom management and health-related quality of life in patients with severe asthma. <strong>Methods:</strong> A cross-sectional correlational study was conducted among 93 patients with severe asthma receiving care at a specialized clinic at the Central Chest Institute of Thailand. Data were collected using standardized instruments, including the Asthma Control Test (ACT), Global Initiative for Asthma (GINA) symptom control criteria, an inhaler technique checklist, the Medication Adherence Report Scale (MARS), the Asthma Self-Management Questionnaire (ASMQ), and the Severe Asthma Questionnaire (SAQ and SAQ-global). Data were analyzed using descriptive statistics and Spearman’s rank correlation coefficient. Correlation strength was interpreted according to Cohen’s criteria (1988). <strong>Results:</strong> Participants demonstrated good asthma control, with a mean ACT score of 22.25 (± 2.68) and a high HRQoL, with a mean SAQ score of 91.33 (± 14.10). SAQ-global scores were substantially higher during asymptomatic conditions than symptomatic conditions. According to Cohen’s criteria, inhaler technique demonstrated a high positive correlation with HRQoL (rₛ = 0.530, p &lt; 0.01), while self-management demonstrated a moderate positive correlation (rₛ = 0.442, p &lt; 0.01). Medication adherence demonstrated a low positive correlation with HRQoL (rₛ = 0.241, p &lt; 0.05). In addition, asthma control assessed by ACT and GINA criteria was significantly associated with overall and symptomatic HRQoL, whereas no significant association was observed during asymptomatic conditions. <strong>Conclusions:</strong> Symptom management was significantly associated with health-related quality of life in patients with severe asthma. Inhaler technique and self-management demonstrated stronger associations with HRQoL than medication adherence. These findings highlight the importance of promoting effective inhaler technique and self-management skills to improve symptom control and enhance long-term quality of life in patients with severe asthma</p> Worawan Khemjan Nathsapass Rawaiklang Copyright (c) 2026 Central Chest Institute of Thailand https://creativecommons.org/licenses/by-nc-nd/4.0 2026-06-08 2026-06-08 2 2 1 9