Postoperative seizures after treatment of spontaneous supratentorial intracerebral hematoma at Sawanpracharak Hospital

Abstract

Objective : To study the relationship of factors associated with seizures in surgical groups of supratentorial intracerebral hematoma patients.

Design : Retrospective analysis

Setting : Department of Surgery, Sawanpracharak Hospital.

Materials and Methods : Retrospective study of registration records of patients with supratentorial intracerebral hematoma were reviewed regarding their age, sex, history of hypertension, diabetes mellitus, smoking, alcoholism, Glasgow Coma Scale, midline shift, size of hematoma, early hydrocephalus and prophylactic antiepileptic drug. Analysis of the relationship of each factor in seizure and non-seizure groups were done by Chi-Square test, Fisher’s exact test and Odd ratio at 95 % confidence level.

Result : Throughout the study period at the hospital, 214 patients with supratentorial intracerebral hematoma underwent surgical evacuation. Factors that were statistically significantly related to seizure and non-seizure were: age (P-0.004), sex [OR 3.62 (1.01-12.98); P=0.037], smoking habit [OR 3.44(1.17-10.13); P=0.02] and early hydrocephalus [5.45 (1.68 -17.66); P=0.01]: and, the factors that were unrelated to seizure and non-seizure included hypertension, diabetes mellitus, alcoholism and use of prophylactic antiepileptic drug.

Conclusion : Seizures that follow surgical treatments of spontaneous supratentorial intracerebral hematoma in this study were related to age, sex, smoking, and early post operative hydrocephalus.