A study of efficacy of Turbutaline in inhibition of labour and Glucocorticoid therapy for the improvement of the lungs of the new born in preterm premature rupture of the membranes at Sawanpracharak Hospital

Abstract

Objective : To study the results of treatments in premature rupture of the membranes in preterm labour.

Setting : The labour room, Department of Obstetrics and Gynecology, Sawanpracharak Hospital.

Design : Descriptive study.

Subject : Preterm pregnant woman with premature rupture of the membranes (PROM) in the labour room of the Department of Obstetrics. Sawanpracharak Hospital from January 2004 to April 2008.

Method : A retrospective study of preterm pregnant women with premature rupture of the membranes with gestational age of 20 - 36 weeks, primigravida and multigravida in 15 - 44 years old who had no medical and obstetrics underlying, no contraindication for inhibition of the labour, and no history of trauma. After confirmation of the premature rupture of the membranes and confirmation of the gestational age by ultrasound. The patient would be admitted into the labour room. After the patient is puton bed rest and a sedative drug would be injected intramuscularly. Turbutaline (bricanyl) was then given intravenous as well as intramuscular steroid therapy.

Results : The patients went on labour within 48 hours with 82.90 percent rate. Average Conclusion time for inhibit of labour was approximately 1.14 ± 1.7 days. According to the procedure of treatment in cases of premature rupture of the membranes in preterm labour, n/e found that the effectiveness of the treatment depended on gestational age. Moreover, neither maternal age nor parity had any statistic significance in relationship to the incidence.

Conclusion : Most cases of PROM went into labour within 24 hours. Delay or inhibition of Keywords the labour at least 48 hours or more, it had benefit in the decrease of respiratory distress syndrome (RDS) in newborns.