Effect of fluid replacement during 60 minutes of moderate-intensity running on splanchnic blood flow

Warot  Rangsimahariwong; Tanat  Tabtieang; Sompol  Sanguanrungsirikul; Natthaya  Chuaypen; Onanong  Kulaputana

Authors

Warot Rangsimahariwong Sports Medicine Program, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand
Tanat Tabtieang Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand
Sompol Sanguanrungsirikul Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand
Natthaya Chuaypen Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand
Onanong Kulaputana King Chulalongkorn Memorial Hospital, the Thai Redcross Society, Bangkok, Thailand

Keywords:

Doppler ultrasound, portal vein, splanchnic hypoperfusion, superior mesenteric artery

Abstract

Background: Exercise-induced splanchnic hypoperfusion has been linked to impaired gastrointestinal function and associated symptoms. The effectiveness of fluid replacement in protecting against splanchnic hypoperfusion is less clear.

Objective: To evaluate the effects of fluid replacement during 60 minutes of moderate-intensity running on the splanchnic blood flow (SBF) using non-invasive Doppler ultrasound.

Methods: Seven healthy men aged 35.4 ± 7.0 years participated in two 60 minute running trials at moderateintensity: the first trial with no water replacement (NW) followed by the second trial with ambient temperature water (28 - 29^oC) replacement (AW). A minimum interval of 48 hours was introduced for the washout period between the trials. SBF was determined by Doppler ultrasound of the superior mesenteric artery (SMA) and portal vein (PV) before and immediately after the run. The core body temperature (Tcore) was also measured rectally.

Results: Running for 60 minutes significantly decreased the SMA flow by 31.2% (425.5 ± 98.0 mL/min to 291.7 ± 79.1 mL/min; P = 0.002) in NW and a non-significant decrease of 9.8% (497.2 ± 144.7 mL/min to 438.4 ± 103.1 mL/min; P = 0.076) in AW. The PV flow decreased by 50.6% (688.7 ± 81.9 mL/min to 333.6 ± 65.6 mL/min; P < 0.001) in NW and a non-significant decrease of 18.6% (718.9 ± 131.3 mL/min to 574.2 ± 145.9 mL/ min; P = 0.069) in AW. At 60 minutes, Tcore showed a significant increase from baseline by 2.19^oC (P < 0.001) in NW and 1.86oC (P < 0.001) in AW, but there was no significant difference in Tcore at 60 minutes between NW and AW.

Conclusion: Fluid replacement during 60 minutes of moderate-intensity running reduces splanchnic hypoperfusion, but not Tcore. This indicates that running-associated gut hypoperfusion may be prevented by fluid replacement during exercise.

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