Peutz-Jeghers syndrome with disappeared pigmentation on lips after operation: A case report

Authors

  • Ra Hyoka Hospital of Pyongyang Medical University in Kim Il Sung University, Democratic People’s Republic of Korea (DPRK)
  • Tae Ho Yu Hospital of Pyongyang Medical University in Kim Il Sung University, Democratic People’s Republic of Korea (DPRK)

Keywords:

Hamartoma, intussusception, intestinal obstruction, lips, polyps, Peutz-Jeghers syndrome

Abstract

Peutz-Jeghers polyps are hamartomas of the small bowel which occur as part of the Peutz-Jeghers syndrome, a rare autosomal dominant condition characterized by gastrointestinal polyps and mucocutaneous melanotic pigmentation. We, hereby, report a case of a young female suffering from this syndrome who presented with hyperpigmentation of the lips and acute intestinal obstruction due to intussusception. An exploratory laparotomy was performed which revealed jejuno-jejunal and jejuno-ileal intussusceptions for which resection and anastomosis was done. There were multiple intraluminal polyps in the jejunum which upon histopathological examination, showed features of Peutz-Jeghers polyp. But, on postoperative day 11, we found the pigmentation on her lips disappeared, the patient behaved well in the postoperative period.

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References

Sreeramulu PN, Agrawal VP. A rare case of multiple intussusceptions in Peutz-Jegherss syndrome. J Med Allied Sci 2013;3:26-8.

Sekmenli T, Afsarlar CE, Bakir S. An unusual presentation of Peutz-Jegherss Syndrome: A case of recurrent jejunal intussusception. Eur J Gen Med 2012; 9:52-5. https://doi.org/10.29333/ejgm/82555

Ozer A, Sarkut P, Ozturk E, Yilmazlar T. Jejunoduodenal intussusception caused by a solitary polyp in a woman with Peutz-Jegherss syndrome: A case report. J Med Case Rep 2014:8:13.

https://doi.org/10.1186/1752-1947-8-13

Kopacova M, Tacheci I, Rejchrt S, Bures J. PeutzJegherss syndrome: diagnostic and therapeutic approach. World J Gastroenterol 2009;15:5397-408. https://doi.org/10.3748/wjg.15.5397

Oncel M, Remzi FH, Church JM, Connor JT, Fazio VW. Benefits of 'clean sweep' in Peutz-Jegherss patients. Colorectal Dis 2004;6:332-5. https://doi.org/10.1111/j.1463-1318.2004.00623.x

Bingi TC, Teja VP, Ramulu B, Manjula B, Vemula R. Peutz-Jeghers's syndrome presenting as multiple intussusceptions: A case report. Indian J Appl Res 2015;5:462-4.

Syngal S, Brand RE, Church JM, Giardiello FM, Hampel HL, Burt RW. ACG clinical guideline: Genetic testing and management of hereditary gastrointestinal cancer syndromes. Am J Gastroenterol 2015;110:223-62. https://doi.org/10.1038/ajg.2014.435

Chisel B, Satish D, Mahavir S, Jitendra SM. Recurrent intussusception secondary to multiple Peutz-Jeghers polyps: An unusual case with review of literature. OGH Reports 2018;7:43-5.

https://doi.org/10.5530/ogh.2018.7.1.9

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Published

2023-08-04

How to Cite

1.
Hyoka R, Ho Yu T. Peutz-Jeghers syndrome with disappeared pigmentation on lips after operation: A case report. Chula Med J [Internet]. 2023 Aug. 4 [cited 2024 Dec. 22];63(1). Available from: https://he05.tci-thaijo.org/index.php/CMJ/article/view/276

Issue

Vol. 63 No. 1 (2019): Chulalongkorn Medical Journal

Section

Case Report

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