Diagnostic accuracy of dual-energy CT to determine urinary tract stone composition: Differentiating between uric acid and non-uric acid urinary tract stone

Authors

  • Pawanaporn Rojanavijitkul Faculty of Medicine, Chulalongkorn University, and King Chulalongkorn Memorial Hospital, The Thai Red Cross Society, Bangkok, Thailand
  • Pattama Tantigate Faculty of Medicine, Chulalongkorn University, and King Chulalongkorn Memorial Hospital, The Thai Red Cross Society, Bangkok, Thailand
  • Supoj Ratchanon Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand
  • Manint Usawachintachit Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand
  • Krit Pongpirul Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand
  • Bundit Chaopathomkul Faculty of Medicine, Chulalongkorn University, and King Chulalongkorn Memorial Hospital, The Thai Red Cross Society, Bangkok, Thailand

Keywords:

Material density images, dual-energy CT, urinary tract stone, uric stone, rapid kilovoltage (kV) switching

Abstract

Background: The urinary tract stone is a worldwide condition with various clinical significances. Optimal treatment requires multiple considerations including stone composition. Dual-energy computed tomography (DECT) has been used to determine uric acid and non-uric acid urinary tract stones.

Objective: To evaluate the diagnostic accuracy of rapid-kilovoltage (kV) switching DECT in differentiating between uric acid and non-uric acid stones compared with reference standard infrared spectroscopy (IRS).

Methods: A prospective study enrolled patients from February 2018 to March 2020 who underwent a DECT scan for urinary tract stone with gif.latex?\geq 3-mm stone (s). Post-processed material-density (MD) images were used to differentiate between uric acid and non-uric acid stones. Exclusion criteria included those with no available IRS result or those with an unclear location of the extracted stone on CT images. Diagnostic accuracy was analyzed using SPSS® v.22.

Results: A total of 28 patients with 35 urinary tract stones were included composing of 2 uric acid and 33 non-uric acid stones. There were 50.0% sensitivity, 96.8% specificity, 50.0% positive predictive value (PPV), 96.8% negative predictive value (NPV) and 93.9% accuracy of MD images compared to IRS.

Conclusion: Rapid-kV switching DECT has high accuracy to determine non-uric acid stones.

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Published

2023-07-17

How to Cite

1.
Rojanavijitkul P, Tantigate P, Ratchanon S, Usawachintachit M, Pongpirul K, Chaopathomkul B. Diagnostic accuracy of dual-energy CT to determine urinary tract stone composition: Differentiating between uric acid and non-uric acid urinary tract stone. Chula Med J [Internet]. 2023 Jul. 17 [cited 2024 May 20];66(1). Available from: https://he05.tci-thaijo.org/index.php/CMJ/article/view/58

Issue

Vol. 66 No. 1 (2022): Chulalongkorn Medical Journal

Section

Original Articles

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