Efficacy and safety of Gymnema inodorum tea consumption in type 2 diabetic patients

Authors

  • Rapong Bespinyowong
  • Suyanee Pongthananikorn
  • Anchalee Chiabchalard

Keywords:

Type 2 diabetes mellitus, Gymnema inodorum, hypoglycemic effect, lipid profiles, safety

Abstract

Background : Diabetes mellitus (DM) is a global epidemic and its prevalence increases in many region of the world. Gymnema inodorum is a medicinal plant that has been used as drug and food for a long time in Thailand. It has hypoglycemic effect in healthy subjects without serious side effects. However, today there has not been any clinical study evaluating its effect in type 2 diabetic patients.

Objective : To evaluate the effect of consumption of G. inodorum tea on clinical outcomes in type 2 diabetic patients.

Design : Before and after quasi-experimental study.

Setting : Diabetes Clinic, Outpatient Department, Lerdsin Hospital, Bangkok.

Materials and Methods : Type 2 diabetic patients voluntarily participated in the study which comprised of 2 consecutive phases. In the controlled phase, the patients received only prescribed drugs (week 0 – week 8) and later in the treatment phase, G. inodorum tea was supplemented (week 8 – week 16). The biochemical parameters, and nutrients and caloric intakes were evaluated at week 0, 8, and 16.

Results : The biochemical parameters including fasting blood sugar (FBS), hemoglobin A1C (HbA1C), total cholesterol (Total-C), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), triglyceride (TG), aspartate aminotransferase (AST), alanine aminotransferase (ALT), and serum creatinine (SCr) did not significantly change throughout the study. So did the nutrient and caloric intakes.

Conclusion : G. inodorum tea had no effect on blood sugar and lipid profiles in this study. It also did not affect hepatic and renal functions.

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Published

2023-09-18

How to Cite

1.
Bespinyowong R, Pongthananikorn S, Chiabchalard A. Efficacy and safety of Gymnema inodorum tea consumption in type 2 diabetic patients. Chula Med J [Internet]. 2023 Sep. 18 [cited 2024 Dec. 26];57(5). Available from: https://he05.tci-thaijo.org/index.php/CMJ/article/view/750