Angiographic findings of Moyamoya

Abstract

Background : Moyamoya is a rare cerebrovascular occlusive condition of unknown etiology which has rarely been described in Thai population. We report angiographic findings and clinical features from a single institution in Thailand.

Objective : Describe angiographic findings and clinical features of moyamoya in patients.

Design : Retrospective descriptive study.

Setting : Department of Radiology, Faculty of Medicine, Chulalongkorn University.

Materials and Methods : Twenty-five patients diagnosed with moyamoya and moyamoyalike by cerebral angiography between 2003-2009 were retrospectively reviewed for clinical manifestation and stenoocclusive lesions according to Suzuki Grading System.

Results : Of the total 25 patients,19 were female (76%), 6 were male (24%), F:M = 3:1. Their median age was 38 years. Five of 6 pediatric patients (83%) presented with ischemic stroke, only one patient (17%) presented with hemorrhagic stroke, Thirteen of 19 (68%) adult patients presented with hemorrhagic stroke, whereas 6/19 (32%) presented with ischemic stroke. From 48 examined cerebral hemispheres, none was grade as stage I (0%), 2 (4.2%) as stage II, 14 (29.2%) as stage III, 19 (39.6%) as stage IV, 12 (25%) as stage V,1(2%) as stage VI.

Conclusions : Clinical presentation and angiographic findings of moyamoya in this study is consistent with prior observations, especially from Japan. However, it differs from the studies in the United States, particularly in clinical manifestation.