Relationship between regimen complexity and medication adherence behavior in Thai elderly with hypertension

Abstract

Background : Only 22 - 25 percent of Thai elderly with hypertension can control their blood pressure. Such failure has been largely ascribed to poor adherence with antihypertensive medication. The regimen complexity is an important factor that influences medication adherence in the elderly.

Objectives : To examine the relationship between regimen complexity and medication adherence behavior in Thai elderly with hypertension.

Setting : Out-patient department of five general hospitals in Thailand.

Research design : Cross-sectional study.

Patients : There were 422 elderly with hypertension who participated in this study.

Methods : The samples were selected based on multi-stage sampling. Data were collected using Medication Regimen Complexity Index and Morisky Medication Adherence Scale. The data were analyzed using descriptive statistics and Pearson’s product moment correlation coefficient.

Results : Regimen complexity had negative correlation with medication adherence behavior (r = -.25, p <.01). More complex prescription such as variety of dosage forms, multiple daily dosing frequencies, and additional instructions for drug administration were related to poor medication adherence behavior (r= -.12, -.21 and -.26, p <.01, respectively).

Conclusions : The data revealed that the elderly who have more complexity of medication regimen are less likely to be adherence. Nurses should take an active role in assessment the regimen complexity and promote medication adherence behavior in Thai elderly with hypertension especially the high risk groups by educating them to overcome the complexities of medication therapy.