Factors Associated with Health-Related Quality of Life in Subarachnoid Hemorrhage in Southern Thailand

Authors

  • Natthanee Pisitthaworaku Division of Neurosurgery, Department of Surgery, Faculty of Medicine, Prince of Songkla University
  • Suphawan Saetan Division of Neurosurgery, Department of Surgery, Faculty of Medicine, Prince of Songkla University
  • Sompit Thongma Division of Neurosurgery, Department of Surgery, Faculty of Medicine, Prince of Songkla University
  • Sukanya Kongchoo Division of Neurosurgery, Department of Surgery, Faculty of Medicine, Prince of Songkla University
  • Jiamjit Kaewsuk Division of Neurosurgery, Department of Surgery, Faculty of Medicine, Prince of Songkla University
  • Busakorn Puntachit Division of Neurosurgery, Department of Surgery, Faculty of Medicine, Prince of Songkla University
  • Phaisit Tabtiang Division of Neurosurgery, Department of Surgery, Faculty of Medicine, Prince of Songkla University
  • Thara Tunthanathip Division of Neurosurgery, Department of Surgery, Faculty of Medicine, Prince of Songkla University

Keywords:

Factors associated with quality of life following subarachnoid hemorrhage

Abstract

Background: Subarachnoid hemorrhage (SAH) leads patients to develop subsequent mortalities, disabilities, and poor health-related quality of life (HRQoL). The present study aimed to investigate factors associated with HRQoL in patients with spontaneous SAH following treatment.
Methods: The present study was a cross-sectional study to assess HRQoL in SAH patients after treatment by the visual analogue scale (VAS) scores. The correlation matrix with Pearson’s correlation among various variables was used to screen a relationship between VAS scores and other variables. Moreover, linear regression analysis was performed in both univariate and multivariable analyses to explore factors associated with the VAS score.
Results: Ninety SAH patients consented and completed the questionnaire. The Hunt and Hess grade, World Federation of Neurological Surgeons grade, and Fisher grade all had negative correlations with VAS scores of -0.712, -0.551, and -0.377, respectively. Following the multiple linear regression with the backward stepwise procedure, the Hunt and Hess grade grade was the only factor in the final model that was linked to HRQoL of SAH patients after treatment
Conclusion: In summary, the present study demonstrated a negative linear correlation between the severity of SAH and patient-reported HRQoL. For general practice, the Hunt and Hess grade could be the most important predictor of HRQoL after treatment in SAH.

Downloads

Download data is not yet available.

References

Sobey CG, Faraci FM. Subarachnoid haemorrhage: what happens to the cerebral arteries?. Clin Exp Pharmacol Physiol 1998;25(11):867-76.

Chan V, Lindsay P, McQuiggan J, Zagorski B, Hill MD, O’Kelly C. Declining Admission and Mortality Rates for Subarachnoid Hemorrhage in Canada Between 2004 and 2015. Stroke 2019;50(1):181-4.

Park SW, Lee JY, Heo NH, Han JJ, Lee EC, Hong DY, et al. Short- and long-term mortality of subarachnoid hemorrhage according to hospital volume and severity using a nationwide multicenter registry study. Front Neurol. 2022;13:952794.

Lindberg M, Angquist KA, Fodstad H, Fugl-Meyer AR. Self-reported prevalence of disability after subarachnoid haemorrhage, with special emphasis on return to leisure and work. Br J Neurosurg 1992;6(4):297- 304.

Greebe P, Rinkel GJ, Hop JW, Visser-Meily JMA, Algra A. Functional outcome and quality of life 5 and 12.5 years after aneurysmal subarachnoid haemorrhage. J Neurol 2010;257(12):2059-64.

Meyer B, Ringel F, Winter Y, Spottke A, Gharevi N, Dams J, et al. Health-related quality of life in patients with subarachnoid haemorrhage. Cerebrovasc Dis 2010;30(4):423-31.

von Vogelsang AC, Burström K, Wengström Y, Svensson M, Forsberg C. Health-related quality of life 10 years after intracranial aneurysm rupture: a retrospective cohort study using EQ-5D. Neurosurgery 2013;72(3):397-406.

Sungkaro K, Tunthanathip T, Taweesomboonyat C, Kaewborisutsakul A. Surgical outcomes of patients after treatment of ruptured anterior communicating artery aneurysms: “real-world” evidence from southern Thailand. Chin Neurosurg J. 2021;7(1):42.

Taweesomboonyat C, Tunthanathip T, Kaewborisutsakul A, Saeheng S, Oearsakul T, Riabroi K, et al. Outcome of Ruptured Posterior Communicating Artery Aneurysm Treatment Comparing Between Clipping and Coiling Techniques. World Neurosurg. 2019;125:e183-8.

Hauser K, Walsh D. Visual analogue scales and assessment of quality of life in cancer. J Support Oncol 2008;6(6):277-82.

Hilari K, Boreham LD. Visual analogue scales in stroke: what can they tell us about health-related quality of life?. BMJ Open 2013;3(9):e003309.

Pickard AS, Knight SJ. Proxy evaluation of healthrelated quality of life: a conceptual framework for understanding multiple proxy perspectives. Med Care 2005;43(5):493-9

Tunthanathip T, Oearsakul T, Tanvejsilp P, Sae-Heng S, Kaewborisutsakul A,et al. Predicting the Healthrelated Quality of Life in Patients Following Traumatic Brain Injury. Surg J (N Y) 2021;7(2):e100-10

Kim JH. Multicollinearity and misleading statistical results. Korean J Anesthesiol 2019;72(06):558–69

Yoo W, Mayberry R, Bae S, Singh K, Peter He Q, Lillard JW Jr. A study of effects of multicollinearity in the multivariable analysis. Int J Appl Sci Technol 2014;4(5):9–19

Taufique Z, May T, Meyers E, Falo C, Mayer SA, Agarwal S, et al. Predictors of Poor Quality of Life 1 Year After Subarachnoid Hemorrhage. Neurosurgery 2016;78(2):256-64.

Kronvall E, Sonesson B, Valdemarsson S, Siemund R, Säveland H, Nilsson OG. Reduced Quality of Life in Patients with Pituitary Dysfunction After Aneurysmal Subarachnoid Hemorrhage: A Prospective Longitudinal Study. World Neurosurg 2016;88:83-91.

Passier PE, Visser-Meily JM, Rinkel GJ, Lindeman E, Post MW.. Determinants of health-related quality of life after aneurysmal subarachnoid hemorrhage: a systematic review. Qual Life Res 2013;22(5):1027- 43.

Golanov EV, Bovshik EI, Wong KK, Pautler RG, Foster CH, Federley RG, et al. Subarachnoid hemorrhage - Induced block of cerebrospinal fluid flow: Role of brain coagulation factor III (tissue factor). J Cereb Blood Flow Metab. 2018;38(5):793-808.

Tunthanathip T. Health Economic Evaluation in Neurosurgery. In: Tunthanathip T. ed. Translational Medicine in Neurosurgery. Bangkok: Sahamit Pattana printing; 2022: 239-72.

Shmueli A. The Visual Analog rating Scale of health related quality of life: an examination of end-digit preferences. Health Qual Life Outcomes 2005;3:71.

Tunthanathip T, Sae-Heng S, Oearsakul T, Kaewborisutsakul A, Taweesomboonyat C. Economic impact of a machine learning-based strategy for preparation of blood products in brain tumor surgery. PLoS One 2022;17(7):e0270916.

Tunthanathip T, Duangsuwan J, Wattanakitrungroj N, Tongman S, Phuenpathom N. Comparison of intracranial injury predictability between machine learning algorithms and the nomogram in pediatric traumatic brain injury. Neurosurg Focus 2021;51(5):E7.

Downloads

Published

2025-10-03

How to Cite

Pisitthaworaku, N., Saetan, S., Thongma, S., Kongchoo, S., Kaewsuk, J., Puntachit, B., Tabtiang, P., & Tunthanathip, T. (2025). Factors Associated with Health-Related Quality of Life in Subarachnoid Hemorrhage in Southern Thailand. Thai Journal of Neurological Surgery, 14(2), 63–72. retrieved from https://he05.tci-thaijo.org/index.php/TJNS/article/view/6719

Issue

Section

Original articles