Olfactory Groove Schwannoma: Two Case Reports
Abstract
Authors presented two very rare cases of a large olfactory groove schwannoma. The theories of their origin are also discussed.
Case 1
A 43-year-old Thai male presented with progressive behavioral change for 2 years. Although he was treated with antipsychotic drugs, his symptoms were worsening after which he also noted decreased olfactory sensation. Radiologic investigations showed a large extra-axial frontal-based tumor, 4.8 x 4.6 x 4.3 cm, causing pressure effect to both frontal lobes. The tumor was totally removed. The pathological examination revealed schwannoma (WHO 2016 grade I). The postoperative course was uneventful. The patient could resume normal daily life, without antipsychotic drugs.
Case 2
A 50-year-old Thai female presented with progressive headache over 2-year duration . In addition, she experienced tight nose and decreased smelling sensation. CT and MRI brain showed a bulky extra-axial frontal based tumor, 5.3 x 5.1 x 4.2 cm, causing pressure effect to the left frontal lobe. The mass extended and penetrated the cribriform plate into the ethmoid sinus. The tumor was subtotally removed. Pathological examination revealed schwannoma (WHO 2016 grade I). No complications occurred, postoperatively. Headache was cured, and the nasal symptoms were improved.
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