การผ่าตัดรักษา Cavernous Carotid Artery Aneurysms Surgical Treatment of Cavernous Carotid Artery Aneurysms
Abstract
Cavernous carotid artery aneurysm is the aneurysm located at cavernous segment of internal carotid artery (ICA). In the past, the main surgery was direct clipping which caused significant cranial nerve deficits and morbidities due to the cavernous sinus exposure, therefore the indirect treatment was developed and almost totally replaced the former treatment. The principle of indirect treatment is parent artery occlusion with or without extracranial-intracranial (EC-IC) bypass. Several procedures for the parent artery occlusion include trapping of aneurysm, proximal occlusion of ICA, and proximal occlusion of common carotid artery. The best procedure is still controversial. Also, the necessity (with or without bypass) and the type (low-flow or high-flow type) of EC-IC bypass is debatable. The data of many literatures were collected and reviewed in this article about the treatment methods and outcomes. From many information, we can conclude that the most appropriate treatment is high-flow bypass with cervical ICA ligation except for the CCAA presented with direct carotid-cavernous fistula (CC fistula) which should be treated with high-flow bypass with trapping of the aneurysm. We also discuss and postulate the possible mechanism of aneurysm thrombosis after cervical ICA ligation.
Downloads
References
Mikabe T, Ogihara R, Tomita S, Kin H, Karasawa H, Watanabe S, et al. Giant intracranial aneurysm visualized by prolonged injection angiography - Case report (authorûs transl). No Shinkei Geka 1980;8:749-53.
Russell SM, Jafar JJ. Microsurgical treatment of intracavernous carotid artery aneurysms. In: Le Roux PD, Winn RH, Newell DW, editors. Management of Cerebral Aneurysms. Philadelphia: Saunders; 2004. p. 711-29.
Welch BG, Eddleman CS, Vance AZ, Samson DS. Management strategies for intracavernous aneurysms. In: Spetzler RF, Kalani MYS, Nakaji P, eds. Neurovascular surgery. 2nd ed. New York: Thieme, 2015:529-37.
Hahn CD, Nicolle DA, Lownie SP, Drake CG. Giant cavernous carotid aneurysms: Clinical presentation in fifty-seven cases. J Neuroophthalmol 2000; 20:253-8.
Silva MN, Saeki N, Hirai S, Yamaura A. Unusual cranial nerve palsy caused by cavernous sinus aneurysms. Clinical and anatomical considerations reviewed. Surg Neurol 1999;52:143-8.
Linskey ME, Sekhar LN, Hirsch WL Jr., Yonas H, Horton JA. Aneurysms of the intracavernous carotid artery: Natural history and indications for treatment. Neurosurgery 1990;26:933-7.
Diaz FG, Ohaegbulam S, Dujovny M, Ausman JI. Surgical alternatives in the treatment of cavernous sinus aneurysms. J Neurosurg 1989;71:846-53.
Hasegawa H, Inoue T, Tamura A, Saito I. Urgent treatment of severe symptomatic direct carotid cavernous fistula caused by ruptured cavernous internal carotid artery aneurysm using high-flow bypass, proximal ligation, and direct distal clipping: Technical case report. Surg Neurol Int 2014;5:49.
Inoue T, Rhoton AL Jr., Theele D, Barry ME. Surgical approaches to the cavernous sinus: A microsurgical study. Neurosurgery 1990;26:903-32.
Dolenc VV. A combined epi- and subdural direct approach to carotid-ophthalmic artery aneurysms. J Neurosurg 1985;62:667-72.
Dolenc VV. Intracavernous carotid artery aneurysm.In: Carter LP, Spetzler RF, editors. Neurovascular surgery. USA: McGraw-Hill;1995: p. 659-672.
Sekhar LN, Burgess J, Akin O. Anatomical study of the cavernous sinus emphasizing operative approaches and related vascular and neural reconstruction. Neurosurgery 1987;21:806-16.
Fukushima T, Day J, Tung H. Intracavernous carotid artery aneurysms. In: Apuzzo MLJ, editor. Brain surgery: complication avoidance and management. USA:Churchill Livingstone;1993: p. 925-944.
Sughrue ME, Saloner D, Rayz VL, Lawton MT. Giant intracranial aneurysms: Evolution of management in a contemporary surgical series. Neurosurgery69:1261-70.
Sekhar LN, Natarajan SK, Ellenbogen RG, Ghodke B. Cerebral revascularization for ischemia, aneurysms, and cranial base tumors.Neurosurgery 2008;62(6 Suppl 3):1373-408.
Parkinson RJ, Bendok BR, OûShaughnessy BA, Shaibani A, Russell EJ, Getch CC, Awad IA, Batjer HH. Temporary and permanent occlusion of cervical and cerebral arteries. Neurosurg Clin N Am 2005; 16(2):249-56.
Surdell DL, Hage ZA, Eddleman CS, Gupta DK, Bendok BR, Batjer HH. Revascularization for complex intracranial aneurysms. Neurosurg Focus 2008;24(2): E21.
Kai Y, Hamada J, Morioka M, Yano S, Mizuno T, Kuroda J, Todaka T, Takeshima H, Kuratsu J. Treatment strategy for giant aneurysms in the cavernous portion of the internal carotid artery. Surg Neurol 2007;67(2): 148-55.
Shimizu H, Matsumoto Y, Tominaga T. Parent artery occlusion with bypass surgery for the treatment of internal carotid artery aneurysms: Clinical and hemodynamic results. Clin Neurol Neurosurg 2010; 112:32-9.
Ashley WW, Amin-Hanjani S, Alaraj A, Shin JH, Charbel FT. Flow-assisted surgical cerebral revascularization. Neurosurg Focus 2008;24(2):E20.
Jafar JJ, Russell SM, Woo HH. Treatment of giant intracranial aneurysms with saphenous vein extracranial- to-intracranial bypass grafting: indications, operative technique, and results in 29 patients. Neurosurgery 2002;51(1):138-44.
Fukushima T, Day J, Tung H. Intracavernous carotid artery aneurysms. In: Apuzzo MLJ, editor. Brain surgery: complication avoidance and management. USA:Churchill Livingstone;1993: p. 925-44.
Little JR, Rosenfeld JV, Awad IA. Internal carotid artery occlusion for cavernous segment aneurysm. Neurosurgery 1989;25:398-404.
Houkin K, Kamiyama H, Kuroda S, Ishikawa T, Takahashi A, Abe H. Long-term patency of radial artery graft bypass for reconstruction of the internal carotid artery. Technical note. J Neurosurg 1999; 90:786-90.
Niiro M, Shimozuru T, Nakamura K, Kadota K, Kuratsu J. Long-term follow-up study of patients with cavernous sinus aneurysm treated by proximal occlusion. Neurol Med Chir (Tokyo) 2000;40:88-96.
Chibbaro S, Tacconi L. Extracranial-intracranial bypass for the treatment of cavernous sinus aneurysms. J Clin Neurosci 2006 Dec;13(10):1001-5.
Murai Y, Teramoto A, Mizunari T, Kobayashi S, Kamiyama H. Treatment of complex internal carotid artery aneurysm using radial artery grafts. Surg Cereb Stroke 2007;35:387-93. [Article in Japanese]
Elhammady MS, Wolfe SQ, Farhat H, Ali Aziz-Sultan M, Heros RC. Carotid artery sacrifice for unclippable and uncoilable aneurysms: endovascular occlusion vs common carotid artery ligation. Neurosurgery 2010;67(5):1431-6.
Murai Y, Mizunari T, Umeoka K, Tateyama K, Kobayashi S, Teramoto A. Radial artery grafts for symptomatic cavernous carotid aneurysms in elderly patients. Neurol India 2011;59:537-41.
Ohtaki S, Mikami T, Iihoshi S, Miyata K, Nonaka T, Houkin K, Mikuni N. Strategy for the treatment of large-giant aneurysms in the cavernous portion of the internal carotid artery. No Shinkei Geka 2013;41(2):107-15. [Article in Japanese] abstract
Menon G, Jayanand S, Krishnakumar K, Nair S. ECIC bypass for cavernous carotid aneurysms: An initial experience with twelve patients. Asian J Neurosurg 2014;9(2):82-8.
Ishishita Y, Tanikawa R, Noda K, Kubota H, Izumi N, Katsuno M, et al. Universal extracranial-intracranial graft bypass for large or giant internal carotid aneurysms: techniques and results in 38 consecutive patients. World Neurosurg 2014;82(1-2):130-9.
Matano F, Murai Y, Mizunari T, Tamaki T, Tateyama K, Koketsu K, et al. Recovery of visual and ophthalmologic symptoms after treating large or giant internal carotid artery aneurysm by high-flow bypass withcervical ligation. World Neurosurg 2017;98:182-8.
Kupersmith MJ, Hurst R, Berenstein A, Choi IS, Jafar J, Ransohoff J. The benign course of cavernous carotid artery aneurysms. J Neurosurg 1992;77(5): 690-3.
Charbel FT, Amin-Hanjani S. Decision making in cerebral revascularization surgery using intraoperative CBF measurements. In: Saleem Abdulrauf, editor. Cerebral revascularization: Techniques in Extracranialto- Intracranial Bypass Surgery. Philadelphia: Elsevier; 2011: p. 45-56.
Tarr RW, Jungreis CA, Horton JA, Pentheny S, Sekhar LN, Sen C, et al. Complications of preoperative balloon test occlusion of the internal carotid arteries: Experience in 300 cases. Skull Base Surg 1991; 1(4):240-4.
Origitano TC, Al-Mefty O, Leonetti JP, DeMonte F, Reichman OH. Vascular considerations and complications in cranial base surgery. Neurosurgery 1994;35(3):351-62.
Lawton MT, Hamilton MG, Morcos JJ, Spetzler RF. Revascularization and aneurysm surgery: current techniques, indications, and outcome. Neurosurgery 1996;38(1):83-92.
Javedan SP, Deshmukh VR, Spetzler RF, Zabramski JM. The role of cerebral revascularization in patients with intracranial aneurysms. Neurosurg Clin N Am 2001;12(3):541-55.
Sekhar LN, Kalavakonda C. Saphenous vein grafts in the management of skull base tumors and aneurysms. Operative techniques in Neurosurgery 1999;2(3):129-41.
Liu JK, Kan P, Karwande SV, Couldwell WT. Conduits for cerebrovascular bypass and lessons learned from the cardiovascular experience. Neurosurg Focus 2003;14(3):e3.
Matsukawa H, Tanikawa R, Kamiyama H, Tsuboi T, Noda K, Ota N, et al. Risk factors for neurological worsening and symptomatic watershed infarction in internal carotid artery aneurysm treated by extracranial- intracranial bypass using radial artery graft. JNeurosurg 2016;125(2):239-46.
Matsukawa H, Tanikawa R, Kamiyama H, Tsuboi T, Noda K, Ota N, et al. Risk Factors for Low-Flow Related Ischemic Complications and Neurologic Worsening in Patients with Complex Internal Carotid Artery Aneurysm Treated by Extracranial to Intracranial High-Flow Bypass. World Neurosurg 2016;85:49-55.
Ota N, Goehre F, Miyazaki T, Kinoshita Y, Matsukawa H, Yanagisawa T, et al. Bypass revascularization applied to the posterior cerebral artery. World Neurosurg 2016;96:460-472.
Matsukawa H, Tanikawa R, Kamiyama H, Tsuboi T, Noda K, Ota N, et al. The Valveless Saphenous Vein Graft Technique for EC-IC High-Flow Bypass: Technical Note. World Neurosurg 2016;87:35-8.
Sekhar LN, Bucur SD, Bank WO, Wright DC. Venous and arterial bypass grafts for difficult tumors, aneurysms, and occlusive vascular lesions: evolution of surgical treatment and improved graft results. Neurosurgery 1999;44:1207-23.
Kivelev J, Tanikawa R, Noda K, Hernesniemi J, Niemel_ M, Takizawa K, et al. Open surgery for recurrent intracranial aneurysms. Techniques and long-term outcomes. World Neurosurg 2016;96:1-9.
lshikawa T, Kamiyama H, Kobayashi N, Tanikawa R, Takizawa K, Kazumata K. Experience from çdoubleinsurance bypass.é Surgical results and additional techniques to achieve complex aneurysm surgery in a safer manner. Surg Neurol 2005;63(5):485-90.
Hongo K, Horiuchi T, Nitta J, Tanaka Y, Tada T, Kobayashi S. Double-insurance bypass for internal carotid artery aneurysm surgery. Neurosurgery 2003;52(3):597-602.
Takahashi JC, Murao K, Iihara K, Nonaka Y, Taki J, Nagata I, et al. Successful çblind-alleyé formation with bypass surgery for a partially thrombosed giant basilar artery tip aneurysm refractory to upper basilar artery obliteration. Case report. J Neurosurg 2007;106:484-7.
Miyamoto S, Funaki T, Iihara K, Takahashi JC. Successful obliteration and shrinkage of giant partiallythrombosed basilar artery aneurysms through a tailored flow reduction strategy with bypass surgery. J Neurosurg 2011;114:1028-36.
Shimizu H, Endo H, Inoue T, Fijimura M, Matsumoto Y, Tominaga T. Surgical treatment of internal carotid artery aneurysms requiring strategic selective clipping or parent artery occlusion/flow alteration. Jpn J Neurosurg 2014;23:721-8.
Murakami K, Shimizu H, Matsumoto Y, Tominaga T. Acute ischemic complications after therapeutic parent artery occlusion with revascularization for complex internal carotid artery aneurysms. Surg Neurol 2009;71(4):434-41.
Sato K, Yamada M, Abe K, Oka H, Kurata A, Fujii K. Tailored flow alteration treatment for intracranial internal carotid artery aneurysms: strategy beyond parent artery occlusion with bypass. Case report. Neurol Med Chir (Tokyo) 2012;52(4):213-6.
Kazumata K, Nakayama N, Nakamura T, Kamiyama H, Terasaka S, Houkin K. Changing treatment strategy from clipping to radial artery graft bypass and parent artery sacrifice in patients with ruptured blister- like internal carotid artery aneurysms. Neurosurgery 2014;10 Suppl 1:66-72; discussion 73.
Yamao Y, Takahashi JC, Satow T, Iihara K, Miyamoto S. Successful flow reduction surgery for a ruptured true posterior communicating artery aneurysm caused by the common carotid artery ligation for epistaxis. Surg Neurol Int 2014;5(Suppl 14):S501-5.
Grand W, Hopkins LN, Siddiqui AH, Mocco J. Vasculature of the Brain and Cranial Base: Variations in clinical anatomy. 2nd ed. New York:Thieme;2016.
Yang K, Park JC, Ahn JS, Kwon DH, Kwun BD, Kim CJ. Characteristics and outcomes of varied treatment modalities for partially thrombosed intracranial aneurysms: a review of 35 cases. Acta Neurochir (Wien) 2014;156(9):1669-75.
van Rooij SB, Bechan RS, Markenstein JE, Sluzewski M, van Rooij WJ. The donut sign: a new angiographic sign for partially thrombosed aneurysms with flowinduced intraluminal thrombus. Interv Neuroradiol 2014;20(1):55-9.
Bederson JB. Hemodynamics and pathophysiology of giant intracranial aneurysms. In: Awad IA, Barrow DL, editors. Giant intracranial aneurysms. Illinois: Park Ridge; 1995. p.13-22.
Rhoton AL Jr. The supratentorial arteries. Neurosurgery 2002;51(4 Suppl):S53-120.
Downloads
Published
How to Cite
Issue
Section
License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Articles in this journal are copyrighted by the x may be read and used for academic purposes, such as teaching, research, or citation, with proper credit given to the author and the journal.use or modification of the articles is prohibited without permission.
statements expressed in the articles are solely the opinions of the authors.
authors are fully responsible for the content and accuracy of their articles.
other reuse or republication requires permission from the journal."