Case report: Cerebellar Tuberculoma Mimicking Malignant Tumor

Authors

  • ธนพงษ์ ลอยเมฆ หน่วยประสาทศัลยศาสตร์ ภาควิชาศัลยศาสตร์ คณะแพทยศาสตร์ จุฬาลงกรณ์มหาวิทยาลัย และโรงพยาบาลจุฬาลงกรณ์ สภากาชาดไทย
  • กฤษณพันธ์ บุณยะรัตเวช หน่วยประสาทศัลยศาสตร์ ภาควิชาศัลยศาสตร์ คณะแพทยศาสตร์ จุฬาลงกรณ์มหาวิทยาลัย และโรงพยาบาลจุฬาลงกรณ์ สภากาชาดไทย

Abstract

This is a 23-year-old female presented with headache due to increased intracranial pressure and cerebellar dysfunction. The radiographic study showed a ring enhancing mass at the left cerebellar hemi- sphere. The patient underwent median suboccipital craniectomy and removal of the mass. Pathological examination revealed tuberculoma which is rare at this location and its radiographic findings often mimick those of other malignant tumors. The authors also reviewed the literature of intracranial tuberculoma in the aspects which are related to this case.

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References

Kelly JD, Teeter LD, Graviss EA, Tweardy DJ. Intracranial tuberculomas in adults: a report of twelve consecutive patients in Houston, Texas. Scand J Infect Dis 2011;43:785-91.

Rock RB, Olin M, Baker CA, Molitor TW, Peterson PK. Central nervous system tuberculosis: pathogenesis and clinical aspects. Clin Microbiol Rev 2008;21: 243-61, table of contents.

Haque R, Chowdhury FH, Islam S, Sarker AC, Haque M. Large cerebellopontine angle tuberculoma: a case report. Neurol Neurochir Pol 2012;46:196-9.

Kim TK, Chang KH, Kim CJ, Goo JM, Kook MC, Han MH. Intracranial tuberculoma: comparison of MR with pathologic findings. AJNR Am J Neuroradiol 1995; 16:1903-8.

DeLance AR, Safaee M, Oh MC, Clark AJ, Kaur G, Sun MZ, et al. Tuberculoma of the central nervous system. J Clin Neurosci 2013;20:1333-41.

Thwaites G, Fisher M, Hemingway C, Scott G, Solomon T, Innes J. British Infection Society guidelines for the diagnosis and treatment of tuberculosis of the central nervous system in adults and children. J Infect 2009;59:167-87.

Bernaerts A, Vanhoenacker FM, Parizel PM, Van Goethem JW, Van Altena R, Laridon A, et al. Tuberculosis of the central nervous system: overview of neuroradiological findings. Eur Radiol 2003;13: 1876-90.

Bayindir C, Mete O, Bilgic B. Retrospective study of 23 pathologically proven cases of central nervous system tuberculomas. Clin Neurol Neurosurg 2006; 108:353-7.

Salaskar AL, Hassaneen W, Keenan CH, Suki D. Intracranial tuberculoma mimicking brain metastasis. J Cancer Res Ther 2015;11:653.

Escobedo-Melendez G, Portillo-Gomez L, Andrade- Ramos MA, Bocanegra D, Mercado-Pimentel R, Arredondo L, et al. Posterior fossa tuberculoma in a Huichol native Mexican child: a case report. BMC Res Notes 2014;7:919.

Sumer S, Koktekir E, Demir NA, Akdemir G. Intracranial giant tuberculoma mimicking brain tumor: a case report. Turk Neurosurg 2015;25:337-9.

Suslu HT, Bozbuga M, Bayindir C. Cerebral tuberculoma mimicking high grade glial tumor. Turk Neurosurg 2011;21:427-9.

Peng J, Ouyang Y, Fang WD, Luo TY, Li YM, Lv FJ, et al. Differentiation of intracranial tuberculomas and high grade gliomas using proton MR spectroscopy and diffusion MR imaging. Eur J Radiol 2012;81:4057-63.

Sadashiva N, Tiwari S, Shukla D, Bhat D, Saini J, Somanna S, et al. Isolated brainstem tuberculomas. Acta Neurochir (Wien) 2017;159:889-97.

Rajshekhar V. Surgery for brain tuberculosis: a re-view. Acta Neurochir (Wien) 2015;157:1665-78.

Helmy A, Antoun N, Hutchinson P. Cerebral tuberculoma and magnetic resonance imaging. J R Soc Med 2011;104:299-301.

Meltzer E, Moussawi K. Intracranial Tuberculoma in a Patient With Untreated Human Immunodeficiency Virus. JAMA Neurol 2017;74:356-7.

Yaramis A, Gurkan F, Elevli M, Soker M, Haspolat K, Kirbas G, et al. Central nervous system tuberculosis in children: a review of 214 cases. Pediatrics 1998;102:E49.

Global tuberculosis control: surveillance, planning, financing. WHO report 2007. Geneva: World Health Organization (WHO/HTM/TB/2007.376).

Yanai H, Uthaivoravit W, Panich V, Sawanpanyalert P, Chaimanee B, Akarasewi P, et al. Rapid increase in HIV-related tuberculosis, Chiang Rai, Thailand, 1990-1994. AIDS 1996;10:527-31.

Sachdeva D, Bishnoi I, Jagetia A, Rathore L, Agarwal A, Batra V, et al. Intraventricular Tuberculoma in a Child: A Rare Location. Pediatr Neurosurg 2017; 52:93-7.

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Published

2025-10-04

How to Cite

ลอยเมฆ ธ., & บุณยะรัตเวช ก. (2025). Case report: Cerebellar Tuberculoma Mimicking Malignant Tumor. Thai Journal of Neurological Surgery, 8(1), 21–16. retrieved from https://he05.tci-thaijo.org/index.php/TJNS/article/view/6779

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Original articles