Factors affecting preterm birth of pregnant women at Aranyaprathet Hospital
Main Article Content
Abstract
Introduction: Preterm birth is an important public health problem in Thailand. It is a major of death in newborns. Globally, more than one per 10 babies are born prematurely, and approximately 15 million (11 percent) are born before 37 weeks of age, which reduces the quality of life for both infants and mothers. Therefore, this research is extremely important. To help protect and reduce risk factors that cause premature birth in pregnant women receiving treatment at Aranyaprathet Hospital.
Objectives: To study factors affecting premature birth in pregnant women at Aranyaprathet Hospital.
Methods: Data were collected on 185 pregnant women who gave birth prematurely and 185 who gave birth at full term, totaling 370 women who received treatment at Aranyaprathet Hospital. Data was collected from 1 January 2021 to 31 December 2023.
Results: From baseline characteristic it was found that the median age of the premature birth group was 28 years, 6 percent had diabetes mellitus, and the median body mass index was 22.2 kg/m2. Blood concentration levels of both hemoglobin and hematocrit in premature birth group, the values were lower than those in the full-term birth group. Pregnant women with a bachelor’s degree or higher have a 2.51 times greater chance of giving birth prematurely. Pregnant women with a history of high blood pressure have a 6.17 times greater risk of giving birth prematurely [aOR: 6.17 (95%CI : 1.19-32.11), P-value = 0.03]. Pregnant women with a history of previous preterm birth have a 7.49 times higher risk of preterm birth [aOR: 7.49 (95%CI : 2.36-23.75), P-value = 0.03]. As for prenatal care less than 8 times, the risk of premature birth is 7.49 times [aOR: 7.49 (95%CI : 2.36-23.75), P-value <0.001]. Complication of diabetes during pregnancy have a higher risk of 2.62 times more likely to be born prematurely [aOR: 2.62 (95%CI : 1.61-4.26), P-value = 0.002] and infections during pregnancy such as hepatitis B infection, vaginitis, cystitis and COVID-19 infection have a 24.65 times greater risk of premature birth [aOR: 24.65 (95%CI : 3.19-190.53), P-value = 0.002]
Conclusion: Factors affecting premature birth from this research include women who have completed a bachelor’s degree, History of previous premature birth, underlying disease is high blood pressure. gestational diabetes, number of prenatal care visits less than 8 times and infection during pregnancy.
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References
Howson CP, Kinney MV, McDougall L, Lawn JE. Born too soon: preterm birth matters. Reprod Health. 2013;10 Suppl 1(Suppl 1):S1.
Beck S, Wojdyla D, Say L, Betran AP, Merialdi M, Requejo JH, et al. The worldwide incidence of preterm birth: a systematic review of maternal mortality and morbidity. Bull World Health Organ. 2010;88(1):31-8.
Saigal S, Doyle LW. An overview of mortality and sequelae of preterm birth from infancy to adulthood. Lancet. 2008;371(9608):261-9.
Lawn JE, Kinney MV, Belizan JM, Mason EM, McDougall L, Larson J, et al. Born Too Soon: Accelerating actions for prevention and care of 15 million newborns born too soon. Reproductive Health. 2013;10(1):S6.
กรมอนามัย.ข้อมูลการฝากครรภ์สำหรับบุคลากรสาธารณสุข 2565;2-3
วรพงศ์ ภู่พงศ์. Untold Treatment of Preterm Labor. การประชุมวิชาการราชวิทยาลัยสูติแพทย์แห่งประเทศไทย 2562;62:1-3.
Gestational Hypertension and Preeclampsia: ACOG Practice Bulletin, Number 222. Obstetrics & Gynecology. 2020;135(6):e237-e60.
Gill SK, Broussard C, Devine O, Green RF, Rasmussen SA, Reefhuis J. Association between maternal age and birth defects of unknown etiology: United States, 1997-2007. Birth Defects Res A Clin Mol Teratol. 2012;94(12):1010-8.
Hypertension in pregnancy. Report of the American College of Obstetricians and Gynecologists’ Task Force on Hypertension in Pregnancy. Obstet Gynecol. 2013;122(5):1122-31.
Association AD. Standards of Medical Care in Diabetes—2022 Abridged for Primary Care Providers. Clinical Diabetes. 2022;40(1):10-38.
Recommendations to prevent and control iron deficiency in the United States. Centers for Disease Control and Prevention. MMWR Recomm Rep. 1998;47(Rr-3):1-29.
Freedman, D.S., Horlick, M. & Berenson, G.S., 2013. A comparison of the Slaughter skinfold-thickness equations and BMI in predicting body fatness and cardiovascular disease risk factor levels in children. Am. J. Clin. Nutr., 98(6), pp.1417–24.
Cunningham FG, Leveno KJ, Bloom SL, Dashe JS, Hoffman BL, Casey BM, et al. Preterm Birth. Williams Obstetrics, 25e. New York, NY: McGraw-Hill Education; 2018.
พรทิพย์ เรืองฤทธิ์. ปัจจัยเสี่ยงต่อการเกิดภาวะเจ็บครรภ์คลอดก่อนกำหนดของสตรีตั้งครรภ์ โรงพยาบาลแม่สรวย จังหวัดเชียงราย: เชียงรายเวชสาร.ปีที่ 14 ฉบับที่ 1/2565
Kinpoon K, Chaiyarach S. The Incidence and Risk Factors for Preterm Delivery in Northeast Thailand. Thai Journal of Obstetrics and Gynaecology. 2021;29(2):100-11.
Zhang Y-P, Liu X-H, Gao S-H, Wang J-M, Gu Y-S, Zhang J-Y, et al. Risk Factors for Preterm Birth in Five Maternal and Child Health Hospitals in Beijing. PLOS ONE. 2012;7(12):e52780.
Kinjyo Y, Kinjo T, Mekaru K, Nagai Y, Moromizato T, Ohata T, et al. Risk Factors of Preterm Birth in Okinawa Prefecture, the Southernmost Island Prefecture of Japan. Matern Child Health J. 2023;27(1):92-100.
Mehta PM, Wang MC, Cameron NA, Freaney PM, Perak AM, Shah NS, et al. Association of Prepregnancy Risk Factors With Racial Differences in Preterm Birth Rates. Am J Prev Med. 2023;65(6):1184-6.
Gurung A, Wrammert J, Sunny AK, Gurung R, Rana N, Basaula YN, et al. Incidence, risk factors and consequences of preterm birth – findings from a multi-centric observational study for 14 months in Nepal. Archives of Public Health. 2020;78(1):64.