FACTOR AFFECTING FATALITY WITH COVID-19 PATEINTS IN KHON KAEN PROVINCE
Keywords:
COVID-19 infection, factors, fatalityAbstract
Although the epidemic of coronavirus disease 2019 (COVID-19) has decreased, people still die of this disease daily. This retrospective study aimed to determine factors affecting fatality among COVID-19 patients in Khon Kaen province. The subjects were 612 patients with COVID-19 infections who received treatment at a hospital in Khon Kaen province from January 1 to December 15, 2022. They were divided into the study group, with 204 deaths from severe pneumonia due to COVID-19 infection and 408 recovery cases in the control group. The research tool was a data recording form. Data were analyzed by descriptive statistics, the chi-square test, and multiple logistic regression analysis.
Factors affecting fatality with COVID-19 patients statistically significant were: older than 60 years (ORadj 55.23, 95% CI = 28.77–106.05, p-value < 0.001), with underlining diseases such as pulmonary tuberculosis (ORadj 11.80, 95% CI = 2.54–54.73, p-value 0.002), diabetes mellitus (ORadj 9.07, 95% CI = 1.52–54.28, p-value 0.016), hypertension (ORadj 4.29, 95% CI = 1.59–11.60, p-value 0.004), and had not been vaccinated (ORadj 2.00, 95% CI = 1.14 – 3.49, p-value 0.015), respectively.
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References
Isaranuwatchai W, Teerawattananon Y, Butchon R, Sukmanee J, Karunayawong P, Saeraneesopon T, et al. Understanding the impact of COVID-19 to improve our health care system responses: Turning crisis into opportunities. Nonthaburi: Health Systems Research Institute; 2022. [in Thai].
Notification of the Ministry of Public Health B.E. 2565 (2022) Title: Repealed Designation and Main Symptoms of Dangerous Communicable Diseases (Issue 3) B.E. 2563 (2020), Government Gazette Volume 139, Special part 223 Ngor. (20 November 2022). [in Thai].
World Health Organization. Statement on the fifteenth meeting of the IHR (2005) Emergency Committee on the COVID-19 pandemic [online] 2023 [cited 2023 May 10]. Available from: https://www.who.int/news/item/05-05-2023-statement-on-the-fifteenth-meeting-of-the-international-health-regulations-(2005)-emergency-committee-regarding-the-coronavirus-disease-(covid-19)-pandemic?fbclid=IwAR2kx6dnww1GG0AT_v7NVzxNw05kFcfOZjtlMlPrpwru3zZHfjRFKcrIm8I
Department of Disease Control, Ministry of Public Health. The weekly situation of COVID-19 patients in Thailand [online] 2023 [cited 2023 May 10]. Available from: https://ddc. moph.go.th/covid19-dashboard/ [in Thai].
Thaicharoen S, Muenrat S, Koyadun S, Saengsuwan L. Risk factors for mortality of coronavirus disease 2019 (COVID-19) patients, Surat Thani province, Thailand. Weekly Epidemiological Surveillance Report 2022; 53(7): 93-101. [in Thai].
Pratipanawat P. Factors of Affecting fatality with COVID-19 patients in Kalasin Hospital. Journal of Health and Environmental Education 2022; 7(1): 64-71. [in Thai].
Hippisley-Cox J, Coupland CA, Mehta N, Keogh RH. Risk prediction of covid-19 related death and hospital admission in adults after covid-19 vaccination: national prospective cohort study. The BMJ 2021; 374(n2244): 1–14.
Bhaskaran K, Bacon S, Evans SJ, Bates CJ, Rentsch CT, MacKenna B. Factors associated with deaths due to COVID-19 versus other causes: population-based cohort analysis of UK primary care data and linked national death registrations within the OpenSAFELY platform. The Lancet Regional Health – Europe 2021; 6: 1-13.
Center for disease control and prevention. StatCalc: Statistical Calculators Unmatched Case-Control [online] 2022 [cited 2023 May 10]. Available from: https://www.cdc.gov/ epiinfo/user-guide/statcalc/unmatche dcasecontrol.html
Kelsey JL, Whittemore AS, Evans AS, Thompson WD. Methods in Observational Epidemiology. Oxford: Oxford University Press; 1996.
Institute of Geriatric Medicine, Department of Medical Services, Ministry of Public Health. Geriatric syndromes care guideline. Bangkok: Is August; 2015. [in Thai].
Pijls BG, Jolani S, Atherley A, Derckx RT, Dijkstra JIR, Franssen GHL, et al. Demographic risk factors for COVID-19 infection, severity, ICU admission and death: a meta-analysis of 59 studies. BMJ Open 2021; 11(e044640): 1-10.
Hoffmann M, Kleine-Weber H, Schroeder S, Kruger N, Herrler T, Erichsen S, et al. SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically proven protease inhibitor. Cell 2020; 52(5): 731- 733.
Parolina L, Pshenichnaya N, Vasilyeva I, Lizinfed I, Urushadze N, Guseva V, et al. Clinical characteristics of COVID - 19 in patients with tuberculosis and factors associated with the disease severity. Int J Infect Dis 2022; 124 (Suppl 1): S82-89.
Aggarwal AN, Agarwal R, Dhooria S, Prasad KT, Sehgal IS, Muthu V. Active pulmonary tuberculosis and coronavirus disease 2019: A systematic review and meta-analysis. PLoS ONE 2021; 16(10): 1-21.
Du P, Li D, Wang A, Shen S, Ma Z, Li X. A Systematic Review and Meta-Analysis of Risk Factors Associated with Severity and Death in COVID-19 Patients. Can J Infect Dis Med Microbiol 2021; 2021: 1-12.
Banchongcharoenlert S, Chumchuen P. Case Fetal Rate and Factors Associated with Deaths due to COVID-19 in Damnoen Saduak Hospital, Ratchaburi Province. Journal of Research for Health Improvement and Quality of Life 2022; 2(1): 25–36. [in Thai].
Working Group to Monitor Vaccine Effectiveness against Coronavirus Disease 2019, Department of Disease Control, Ministry of Public Health. Effectiveness of the coronavirus disease 2019 [COVID-19] vaccine in Thai health care workers, July 2021. Weekly Epidemiological Surveillance Report 2021; 52(35): 509 - 511.
[in Thai] .
Vasileiou E, Simpson CR, Shi T, Ker S, Agrawal U, Akbari A, et al. Interim findings from first-dose mass COVID-19 vaccination roll-out and COVID-19 hospital admissions in Scotland: a national prospective cohort study. The Lancet 2021; 397(10285):1646-1657.
Chirico F, Teixeira da Silva JA, Tsigaris P, Sharun K. Safety & effectiveness of COVID-19 vaccines: A narrative review. Indian J Med Res 2022; 155(1): 91-104.
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