Risk Factors Associated with Severity of Coronavirus Disease 2019 Patients, Phangnga Province
Keywords:
Coronavirus disease 2019, Risk factor, Patient severity, Multivariate logistic regressionAbstract
This cross- sectional research aimed to 1) examine the epidemiological factors of patients with Coronavirus disease 2019 (COVID-19) 2) analyze the clinical characteristics of patients with COVID-19 3) analyze risk factors associated with the severity of the COVID-19 patients. A total of 944 study samples were COVID-19 patients who received services at Phang Nga Hospital and Takua Pa Hospital between 1 April 2021 - 30 September 2022. Descriptive statistics was used to analyze the epidemiological and clinical characteristics of COVID-19 patients. Analytical statistics of multivariate logistic regression (Odds Ratio และ 95% confidence interval) was applied to analyze risk factors associated with the severity of the COVID-19 patients The results of the analysis of risk factors that were statistically significantly associated with the severity of COVID-19 patients using multiple logistic regression methods included Thai nationality (aOR 5.35, 95% CI 1.08 – 26.57, P-value = 0.04), blood oxygen concentration < 95 % (aOR 8.58, 95% CI 3.76 – 19.55, P-value < 0.01), radiographic results of abnormal lung tissue lesions (aOR 60.66, 95 % CI 29.38 – 125.22, P-value < 0.01), Lymphocyte < 28 percent (aOR 2.66, 95% CI 1.36 – 5.18, P-value < 0.01), shortness of breath (aOR 9.72, 95% CI 4.74 – 19.94, P- value < 0.01), stroke (aOR 28.28, 95% CI 5.49 – 145.76, P-value < 0.01) and cancer (aOR 25.25, 95% CI 1.70 – 375.11, P-value = 0.01). These research findings can be exploited as a database and pivotal knowledge in various aspects of COVID-19 including epidemiology, clinical characteristics of patients. risk factors affecting the severity of COVID-19 patients to lead to planning, monitoring, and use in developing guideline and manual of surveillance, diagnosis and treatment for physicians, nurses, and medical technologists, public health personnel and interested persons.
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