Mpox in Neonates and Children: A Review Article
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Abstract
Mpox, caused by the monkeypox virus, has expanded beyond its historical African boundaries, with significant global outbreaks, including a 2022 surge. While traditionally affecting adults, recent cases in neonates and children show more severe complications, including respiratory failure, encephalitis, and sepsis. Children are more vulnerable due to an immature immune system and at higher risk for multi-organ involvement. Prevention focuses on vaccination, personal hygiene, and safe sexual practices, with JYNNEOS® and ACAM2000® vaccines recommended for high-risk groups. Early diagnosis, supportive care, and antiviral treatment are crucial in managing severe cases. This review highlights differences in disease severity between adults and children and outlines key prevention and treatment strategies
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