Risk Factors for Mortality of Coronavirus Disease 2019 (COVID-19) Patients, Surat Thani province, Thailand
Keywords:
coronavirus disease 2019, mortality, risk factor, multivariate logistic regressionAbstract
Introduction: Coronavirus disease 2019 (COVID-19) an emerging infectious disease, caused by the SARS-CoV-2 virus has been a pandemic since March 2020. The April outbreak during 1 April–31 December, 2021 in Surat Thani Province found 28,809 cumulative confirmed cases, 159 cumulative deaths, representing case fatality rate of 0.55%. This cross-sectional study aimed to 1) describe epidemiology of COVID-19 patients and 2) analyze risk factors for mortality of COVID-19 patients.
Methods: The study samples consisted of 477 cases, were randomly selected from the database of patients diagnosed with COVID-19, aged ≥18 years, which the April outbreak wave occurred in Surat Thani Province during April 1–December 31, 2021.
Results: Research results showed that the majority of the study subjects were female (55.8 %), aged ≥ 60 years (36.7%), unvaccinated COVID-19 (55.4%) and chronic comorbidity (40.7%). Risk factors influencing mortality statistically (P-value < 0.05), by multivariable logistic regression analysis, were aged ≥ 60 years (aOR 36.15, 95% CI 4.44–18.79), chronic comorbidity (aOR 31.70, 95% CI 4.17–19.16) diabetes mellitus (aOR 7.53, 95% CI 1.50–11.51), chronic kidney disease (aOR 4.57, 95% CI 1.23–117.51) and incomplete COVID-19 vaccination (aOR 35.59, 95% CI 12.58–149.84).
Conclusion and Recommendation: This research concluded that older age, chronic comorbidities, diabetes mellitus, chronic kidney disease and incomplete COVID-19 vaccination were important risk factors for death among COVID-19 patients. Therefore, COVID-19 patients with risk factors should receive rapid diagnosis and proper management. Risk groups should be actively speed up vaccination to cover them.
References
World Health Organization. Novel Corona Virus 2019 [Online]. 2020 [cited 2022 Jan 5]. Available from: https://www.who.int/emergencies/diseases/novel-coronavirus-2019
กรมควบคุมโรค. แนวทางเวชปฏิบัติ การวินิจฉัย ดูแล รักษา และป้องกันการติดเชื้อในโรงพยาบาล กรณีโรคติดเชื้อไวรัส โคโรนา 2019 [ออนไลน์]. 2563 [เข้าถึงเมื่อ 5 มกราคม 2565]. เข้าถึงจาก: https://ddc.moph.go.th/viralpneumonia/g_health_care.php
World Health Organization. COVID-19 as a Public Health Emergency of International Concern (PHEIC) under the IHR. [Online]; 2020 [cited 2022 Jan 5]. Available from: https://extranet.who.int/sph/COVID-19-public-health-emergency-international-concern-pheic-under-ihr
ศูนย์ปฏิบัติการภาวะฉุกเฉิน กรมควบคุมโรค. รายงานสถานการณ์โรคติดเชื้อไวรัสโคโรนา 2019 [อินเทอร์เน็ต]. [เข้าถึงเมื่อ 5 มกราคม 2565]. เข้าถึงได้จาก https://ddc.moph.go.th/viralpneumonia/file/situation/situation-no544-300664.pdf
Guan W, Ni Z, Hu Y, Liang W, Ou C, He J, et al. Clinical Characteristics of Coronavirus Disease 2019 in China [Internet]. The new england journal of medicine. 2020 [cited 2022 Jan 10];41:1–10. Available from: https://doi.org/10.1056/NEJMoa2002032
Ianleng K, Yanopas A, Phaopraphat K. Nursing Care for COVID-19 Patients in Cohort Ward, Siriraj Hospital. Siriraj Medical Bulletin. 2021; 14: 12–8.
อำพวรรณ์ ยวนใจ, อุ่นเรือน กลิ่นขจร, สุพรรษา วรมาลี, จรินทร์รฐา วัชระเกษมสุนทร. ผู้ป่วยโรคติดเชื้อ Coronavirus disease 2019: รายงานผู้ป่วย. เวชบันทึกศิริราช. 2563; 13:155–63.
Chen N, Zhou M, Dong X, Qu J, Gong F, Han Y. et al. Epidemiology and Clinical Characteristics of 99 Cases of 2019 Novel Coronavirus Pneumonia in Wuhan, China: A Descriptive Study. Lancet 2020;39:507–13.
Goyal P, Choi JJ, Pinheiro LC, Schenck EJ, Chen R, Jabri A. Clinical Characteristics of COVID-19 in New York City. The new england journal of medicine NEJM.org [Online]. 2020 [cited 2022 Jan 16]. Available from: doi: 10.1056/NEJMc2010419
อนุตรา รัตน์นราทร. ลักษณะทางคลินิกและภาพรังสีทรวงอกของผู้ป่วยโรคปอดอักเสบจากโควิด 19 ที่สถาบันบำราศนราดูร. วารสารควบคุมโรค. 2563;46:540–50.
Grasselli G, Greco M, Zanella A, et al. Risk Factors Associated with Mortality Among Patients With COVID-19 in Intensive Care Units in Lombardy, Italy. JAMA Intern Med [Online]. 2020 [cited 2022 Jan 16];180(10):1345–55. Available from: https://pubmed.ncbi.nlm.nih.gov/32667669/
Elliott J, Bodinier B, Zanella A, Whitaker M, et al. COVID-19 mortality in the UK Biobank cohort: revisiting and evaluating risk factors. European Journal of Epidemiology [Online]. 2021 [cited 2022 Jan 16];36:299–309. Available from: https://doi.org/10.1007/s10654-021-00722-y
Orwa A, Ballouze R, Ooi P, Ghadzi SMS. Risk factors for mortality among COVID-19 patients. Diabetes Research and Clinical Practice [Online]. 2020 [cited 2022 Jan 16]. Available from: https://www.sciencedirect.com/science/article/pii/S0168822720305453
กรมการแพทย์ กระทรวงสาธารณสุข. แนวทางเวชปฏิบัติ การวินิจฉัย ดูแลรักษา และป้องกันการติดเชื้อในโรงพยาบาล กรณีโรคติดเชื้อไวรัสโคโรนา 2019 (COVID-19) ฉบับปรับปรุง 28 มกราคม 2564 [อินเทอร์เน็ต]. [เข้าถึงเมื่อ 1 กุมภาพันธ์ 2565]. เข้าถึงได้จาก https://covid19.dms.go.th/backend/Content/Content_File/Covid_Health/Attach/25640129094049AM_CPG_COVID_v.11.1.pdf
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