Situation of Syphilis in Thailand, 2025 – Data as of September 4, 2025

Authors

  • Kanidta Poobua Division of Epidemiology, Department of Disease Control, Ministry of Public Health, Thailand
  • Thitipong Yingyong Division of Epidemiology, Department of Disease Control, Ministry of Public Health, Thailand
  • Supiya Jantaramanee Division of Epidemiology, Department of Disease Control, Ministry of Public Health, Thailand

DOI:

https://doi.org/10.59096/wesr.v56i9.6649

Abstract

Highlight

- Syphilis is an infectious disease caused by the bacterium Treponema pallidum, which can be transmitted through multiple routes, including vaginal, anal, and oral sexual contact, blood transfusion, and vertical transmission from mother to fetus via the placenta.

- As of 4 September 2025, a total of 20,968 cases were reported, with a prevalence rate of 31.78 per 100,000 population, and 4 deaths (3 stillbirths and 1 case of congenital syphilis), corresponding to a case fatality rate of 0.02%.

- The prevalence of syphilis has shown a continuous upward trend over the past 10 years, with the number of cases in 2025 exceeding both the five-year median (2020–2024) and that of the previous year (2024).

- Recommendation for prevention and control measures including the promotion of consistent condom use, screening and treatment population at risk and their sexual partners, Among pregnant woman early antenatal care before 12 weeks of gestation including screening and treatment to reduce the risk of mother-to-child transmission.

References

World Health Organization. Syphilis [Internet]. 2025 [cited 2025 Jul 31]. Available from: https://www.who.int/news-room/fact-sheets/detail/syphilis

Ministry of Public Health (TH), Department of Disease Control, Division of Epidemiology. Case definition for communicable diseases surveillance, Thailand, 2020. Nonthaburi: Division of Epidemiology, Department of Disease Control; 2020. (in Thai)

Ministry of Public Health (TH), Department of Disease Control, Division of AIDS, TB and STIs. Guidelines for the management of sexually transmitted infections, 2024. Nonthaburi: Division of AIDS, TB and STIs, Department of Disease Control; 2024. (in Thai)

World Health Organization. Elimination of mother-to-child transmission of HIV, syphilis and hepatitis B [Internet]. [cited 2025 Aug 27]. Available from: https://www.who.int/initiatives/triple-elimination-initiative-of-mother-to-child-transmission-of-hiv-syphilis-and-hepatitis-b

World Health Organization. Implementing the global health sector strategies on HIV, viral hepatitis and sexually transmitted infections, 2022–2030: report on progress and gaps 2024, second edition [Internet]. Geneva: World Health Organization; 2024 [cited 2024 Sep 4]. Available from: https://iris.who.int/bitstream/handle/10665/378246/9789240097872-eng.pdf?sequence=1

Ministry of Public Health (TH), Department of Disease Control, Division of Innovation and Research Services. National program for prevention and control of diseases and health threats, 2022–2026 [Internet]. Nonthaburi: Department of Disease Control; 2022 [cited 2025 Jul 1]. Available from: https://www.oic.go.th/FILEWEB/CABINFOCENTER28/DRAWER068/GENERAL/DATA0000/00000709.PDF (in Thai)

Ministry of Public Health (TH), Department of Disease Control, Division of AIDS, TB and STIs. Annual report 2024. Nonthaburi: Department of Disease Control; 2024. (in Thai)

World Health Organization. Mother-to-child transmission of syphilis [Internet]. [cited 2025 Aug 25]. Available from: https://www.who.int/teams/global-hiv-hepatitis-and-stis-programmes/stis/prevention/mother-to-child-transmission-of-syphilis

Ministry of Public Health (TH), Department of Disease Control, Division of Epidemiology. Behavioral Surveillance System (BSS) 2024: Secondary school students (Grade 8 and 11) and vocational students (Year 2) [Internet]. Nonthaburi: Department of Disease Control; 2024 [cited 2025 Sep 1]. Available from: http://aidsboe.moph.go.th/app/bookup/uploads/2025-08-071801127818.pdf (in Thai)

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Published

2025-09-30

How to Cite

Poobua, K., Yingyong, T., & Jantaramanee, S. (2025). Situation of Syphilis in Thailand, 2025 – Data as of September 4, 2025. Weekly Epidemiological Surveillance Report, 56(9), e6649. https://doi.org/10.59096/wesr.v56i9.6649

Issue

Section

Health situation analysis