Factors Affecting Neonatal Thyroid Hormone Deficiency in the Era of COVID–19 Pandemic, Akat Amnuai District, Sakon Nakhon Province

Authors

  • Preedie Srisamai Akat Amnuai Hospital, Sakon Nakhon Province
  • Jirattikal Suttawanit AkatAmnuai Hospital, Sakon Nakhon Province

Keywords:

Infant, Pregnant woman, Thyroid hormone, Iodized salt, Iodine supplement, high Iodine dietary

Abstract

               In the era of COVID–19 pandemic, Iodine deficiency has an impact on the fetus and pregnant woman’s health, leading to miscarriages and premature births, newborns with underweight, anemic and hypothyroid. This research aimed to study the relationship between personal, social and environmental factors and Thyroid hormone deficiency in infant. The participant consisted of 134 postpartum women with their infant. The data were collected from June to July 2022. The research tool was the interviewing form developed by the researchers according to the health promotion theory for pregnant woman. Data were analyzed by using the frequency, percentage and multiple logistic regressions.

                 The results revealed that 67.7% of samples were pregnant aged 20–34 years, 50.7% took iodized salt before pregnancy, 67.2% consumed iodized salt during pregnancy, 45.5% received iodized salt during antenatal care, 30.6% took folate before pregnancy, 53.0% reached quality criteria of antenatal care and 57.5% took daily iodine supplement. Factors affected the Thyroid hormone deficiency in infant were didn’t eat iodized salt in household, didn’t take folate before pregnant, education level below secondary education and residing in the Sub–district Administrative Organization. The multiple logistic regressions analysis showed that Thyroid hormone deficiency in infants of pregnant women whose husbands drank alcohol and smoked were 0.26 and 0.43 times more than that of pregnant women whose husbands didn’t drink alcohol and didn’t smoke, respectively (ORadj = 0.26, 95%CI 0.10–0.66 and 0.43, 95% CI 0.20–0.94, respectively). Thyroid hormone deficiency in infants of pregnant women with pre–pregnancy malnutrition was 2.59 times more than that of pregnant women with adequate nutrition (ORadj = 2.59, 95%CI 1.17–5.74). Therefore, iodine consumption is important for pregnant woman. The more rigorous monitoring system should be designed to encourage pregnant women taking daily iodine supplement sufficiently.

Author Biographies

Preedie Srisamai, Akat Amnuai Hospital, Sakon Nakhon Province

CDT, Public Health Technical Officer (Professional Level), Akat Amnuai Hospital, Sakon Nakhon
Province

Jirattikal Suttawanit, AkatAmnuai Hospital, Sakon Nakhon Province

Medical Pediatric (Senior Professional Level), AkatAmnuai Hospital, Sakon Nakhon Province

References

World Health Organization. WHO Coronavirus disease (Covid–19) Dashboard [Internet]. 2022 [Cited 2022 Nov 20]. Available form: https://covid19.who.int/

Speer G, Somogyi P. Thyroid complications of SARS and coronavirus disease 2019 (COVID–19). Endocr J 2021;68(2):129–136.

Kianpour M, Aminorroaya A, Amini M, Feizi A, Aminorroaya Yamini S, Janghorbani M. Thyroid–stimulating hormone (TSH) serum levels and risk of spontaneous abortion: A prospective population–based cohort study. ClinEndocrinol (Oxf) 2019;91(1):163–169.

กลุ่มงานสร้างเสริมสุขภาพ.สรุปวิเคราะห์งานควบคุมป้องกันภาวะโรคขาดสารไอโอดีน.สกลนคร:สำนักงานสาธารณสุขจังหวัดสกลนคร; 2564.

Wayne WD, CHAD LC. Biostatistics: A foundation of analysis in the health sciences. 6 th ed. America: John wiley & sons; 1995.

Pregnancy, Childbirth, Postpartum and Newborn Care: A Guide for Essential Practice. Geneva: World Health Organization; 2006.

Nunnally JC. Psychometric theory. New York: McGraw–Hill; 1967.

Alman DG. Practical statistics for medical research. London: Chapman and hall; 1991. p.419–26.

Suplotova LA, Makarova OB, Troshina A. [Neonatal thyrotropin indicatior of monitoring of iodine deficiency severity. What’s level is considered a «cutoff point»?]. Probl Endokrinol (Mosk) 2022;68(6):12–21;2007

Somprasit C, Tanprasertkul C, Rattanasiri T, Saksiriwutth P, Wongkum J,Kovavisarach E, et al. High pre–pregnancy body mass index and the risk of poor obstetrics outcomes among Asian women using BMI criteria for Asians by World Health Organization Western Pacific Region (WPRO): a large cohort study. J Med Assoc Thai 2015;98 (Suppl2):S101–7.

BalharaYP, Deb KS. Impact of alcohol use on thyroid function. Indian J Endocrinol Metab 2013;17(4):580–7.

Rachdaoui N,Sarkar DK.Pathophysiologyof the Effects of Alcohol Abuse on the Endocrine System. Alcohol Res 2017;38(2):255–276.

Punjabi U, Goovaerts I, Peeters K, Van Mulders H, De Neubourg D. Sperm as a Carrier of Genome Instability in Relation to Paternal Lifestyle and Nutritional Conditions. Nutrients 2022;14(15):3155.

Wiersinga WM. Smoking and thyroid. Clin Endocrinol (Oxf) 2013;79(2):145–51.

Sawicka–Gutaj N, Gutaj P, Sowinski J, Wender–Ozegowska E, Czarnywojtek A, Brazert J, et al. Influence of cigarette smoking on thyroid gland—an update. Endokrynol Pol 2014;65(1):54–62.

Noor F, Nessa A,Sharmin A, Yeasmin F, Firoz S, Rahman MH. Body Mass Indexand Serum Thyroid Stimulating Hormone in Third Trimester of Pregnancy. Mymensingh Med J 2021;30(1):69–72.

González–MartínezS,Riestra–Fernández M, Martínez–Morillo E, Avello–Llano N, Delgado–Álvarez E, Menéndez–Torre EL. Nutritional Iodine Status in Pregnant Women from Health Area IV in Asturias (Spain): Iodised Salt Is Enough. Nutrients 2021;13(6):1816.

Huang L, Zhang L, Rao Z, Huang C, Huang H. Dietary iodine intake and urinary iodine concentration during pregnancy in Chengdu, China. Asia Pac J Clin Nutr2021;30(4):643–650.

Tariku WB, Mazengia AL. Knowledge and Utilization of Iodized Salt and Its Associated Factors at Household Level in Mecha District, Northwest Ethiopia. J Nutr Metab 2019;2019:9763830.

Mamo W, Derso T, Nigatu SG. Adequately Iodized Salt Utilization and Associated Factors among Households in Tach Armachio District, Northwest Ethiopia: A Community–Based Cross–Sectional Study. J Nutr Metab 2021;2021:6630450.

Babiz Leko M, Gunjaza I, Pleiz N, Zemunik T. Environmental Factors Affecting Thyroid–Stimulating Hormone and Thyroid Hormone Levels. Int J Mol Sci 2021;22(12):6521.

Downloads

Published

2024-06-25

How to Cite

1.
Srisamai P, Suttawanit J. Factors Affecting Neonatal Thyroid Hormone Deficiency in the Era of COVID–19 Pandemic, Akat Amnuai District, Sakon Nakhon Province. J Sakon Nak Hosp [Internet]. 2024 Jun. 25 [cited 2024 Dec. 23];26(1):53-67. Available from: https://he05.tci-thaijo.org/index.php/JSakonNakHosp/article/view/2772

Issue

Section

Original article