Effects of the Chronic Kidney Disease Progression-Delay Program in Patients with Non–Insulin-Dependent Diabetes Mellitus. at Phon Na Kaeo Hospital, Sakon Nakhon Province

Abstract

          This quasi-experimental study, employing a one-group pretest–posttest design, aimed to evaluate the effects of the Kidney Function Deterioration–Delay Program among patients with non–insulin-dependent diabetes mellitus (NIDDM) at Phon Na Kaeo Hospital, Sakon Nakhon Province. The study population comprised 499 patients with NIDDM receiving care at the hospital. The sample included patients who were unable to achieve adequate glycemic control during the period from 20 July 2025 to 20 October 2025. The intervention tool was the Kidney Function Deterioration–Delay Program. Data collection instruments included a personal information questionnaire, a health care knowledge test, and a self-care behavior assessment form. Data were analyzed using frequency distribution, percentage, mean, standard deviation, and paired t-test.

             Results: The findings demonstrated significant improvements across all measured domains following the intervention. Participants’ knowledge regarding health care practices to delay renal function decline increased significantly after the program (x̄ = 13.29, S.D. = 2.19; t = –11.70, p < .001). Self-care behavior scores related to the prevention of kidney deterioration also improved significantly post-intervention (x̄ = 3.45, S.D. = 0.46; t = –13.63, p < .001). Regarding clinical outcomes, fasting blood sugar (FBS) levels decreased significantly following the intervention (x̄ = 135.09, S.D. = 24.03;

t = 7.92, p < .001). Glycated hemoglobin (HbA1C) levels mirrored this trend, showing a significant reduction post-intervention (x̄ = 7.17, S.D. = 1.16; t = 6.54, p < .001). Additionally the estimated glomerular filtration rate  (eGFR) increased significantly after the program (x̄ = 87.10, S.D. = 15.12; t = –7.39 p < .001), reflecting improved renal function.

        Recommendations: It is recommended that the Kidney Function Deterioration–Delay Program be further promoted and integrated into routine care for diabetic patients at Phon Na Kaeo Hospital to strengthen self-care behavioral modification. Furthermore, the program should be scaled up for implementation in subdistrict health-promoting hospitals, as its broader application has the potential to enhance self-management practices among diabetic patients and reduce the risk of diabetes-related complications.