The Outcomes of Pharmaceutical Care in Patients with New Smear Pulmonary Tuberculosis at Sawankhalok Hospital, Sukhothai Province

Abstract

Abstract

       The appropriated pharmaceutical care for patients with smear pulmonary tuberculosis would promote medicaton adherence and decrease adverse drug evens those leading to success rate in new smear pulmonary tuberculosis patients. The objective of research aimed to examine the outcomes of pharmaceutical care in patients with new smear pulmonary tuberculosis at Sawankhalok hospital, Sukhothai Province. The methods of research was Quasi-experiment research. The samples were 40 new smear pulmonary tuberculosis patients and had treatment success at TB clinic outpatient department, Sawankhalok Hospital between May 29^st 2023 to May 28^st 2024. They were selected using a purposive sampling technique and reached inclusion criteria. Collecting tools were the personal record, the record of  drug related problems: DRPs, the 8-item Morisky Medication Adherence Scale: MMAS-8 (reliability 0.84) and Patient-Reported Outcome Measure of Pharmaceutical Therapy Quality of life: PROMPT-QoL(reliability 0.82). Intervention was Pharmaceutical Care in Patients with New Smear Pulmonary Tuberculosis at Sawankhalok Hospital, Sukhothai Province (IOC 0.83). Personal data and drug related problems were analyzed using descriptive statistics and compared mean of medication adherence and pharmaceutical therapy quality of life by paired t test.

           The results revealed that the percentage of drug related problems was 97.5, after using developed-guideline: Pharmaceutical Care in Patients with New Smear Pulmonary Tuberculosis at Sawankhalok Hospital, Sukhothai Province had good outcomes comparing between the end of intensive phase and treatment success phase significantly including
1) increasing the mean of medication adherence p-value <0.001), and 2)the mean of pharmaceutical therapy quality of life (p-value <0.001).

Conclusion was the Pharmaceutical Care in Patients with New Smear Pulmonary Tuberculosis at Sawankhalok Hospital, Sukhothai Province could increase medication adherence and pharmaceutical therapy quality of life.

          Suggestion: should develop the directly observed therapy and drug related problems following guideline which including the participation of pulmonary tuberculosis family that leading to higher medication adherence achieving goal 90.0 percentages.